Nicotinamide mononucleotide (NMN) is one of the main precursors of nicotinamide adenine dinucleotide (NAD+) — an essential enzyme for various critical cell functions, including metabolism, DNA repair, cell growth and survival. Stimulating NAD+ metabolism with NMN or nicotinamide riboside extends healthspan and mitigates premature ageing diseases in mice. Long-term (12 months) oral administration of NMN suppresses age-associated weight gain, enhances energy metabolism, improves insulin sensitivity and prevents age-linked changes in gene expression. Following treatment, the metabolism and energy levels of older mice resemble those of younger mice.
Potential Health Benefits
- Brain: May improved brain function and protection from neurodegeneration
- Vasculature: May increased neovascularization, capillary density and blood flow.
- Liver: May improved liver function, reduced hepatic steatosis and increased capacity to regenerate
- Muscle: May reduced atrophy. enhanced mitochondrial function and increased physical activity.
- Pancreas: Improved B-cell function, increased insulin secretion and reduced inflammation.
- Adipose Tissue: May reduced dysplipidaemia and prevention of insulin resistance.
- Inflammation: May reduced inflammation and improved immune cell function.
Nicotinamide mononucleotide (NMN) is one of the main precursors of nicotinamide adenine dinucleotide (NAD+) — an essential enzyme for various critical cell functions, including metabolism, DNA repair, cell growth and survival. Stimulating NAD+ metabolism with NMN or nicotinamide riboside extends healthspan and mitigates premature ageing diseases in mice. Long-term (12 months) oral administration of NMN suppresses age-associated weight gain, enhances energy metabolism, improves insulin sensitivity and prevents age-linked changes in gene expression. Following treatment, the metabolism and energy levels of older mice resemble those of younger mice.
Potential Health Benefits
- Brain: May improved brain function and protection from neurodegeneration
- Vasculature: May increased neovascularization, capillary density and blood flow.
- Liver: May improved liver function, reduced hepatic steatosis and increased capacity to regenerate
- Muscle: May reduced atrophy. enhanced mitochondrial function and increased physical activity.
- Pancreas: Improved B-cell function, increased insulin secretion and reduced inflammation.
- Adipose Tissue: May reduced dysplipidaemia and prevention of insulin resistance.
- Inflammation: May reduced inflammation and improved immune cell function.